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Allele : Tamalin<tm2.1Nak> trafficking regulator and scaffold protein tamalin; targeted mutation 2.1, Shigetada Nakanishi

Primary Identifier  MGI:3757981 Allele Type  Targeted
Attribute String  Null/knockout Gene  Tamalin
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  false Is Wild Type  false
molecularNote  Using a targeting vector constructed with C57BL/6 BAC genomic clone, a floxed neo cassette was inserted upstream of exon 5 and an additional lox P site was inserted downstream of exon 7. Cre-mediated recombinated removed the neo cassette and exons 5 through 7 to create a truncated protein detectable by western blot analysis that lacks a complete PDZ dmain and leucine zipper.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Tam<->,
  • Tam<->
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

4 Publication categories