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Allele : Tg(TcraHsv2.3)L118-3Cbn transgene insertion L118-3, Frank Carbone

Primary Identifier  MGI:3758621 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(TcraHsv2.3)L118-3Cbn
Is Recombinase  false Is Wild Type  false
molecularNote  Rearranged Tcra and Tcrb derived from HSV-1 glycoprotein B specific CTL clone HSV2.3 were placed under the control of a 2 kb fragment of the H-2Kb and a 700 bp fragment including the Igh enhancer. The two constructs were coinjected into F1 embryo zygotes resulting in the establishment of two founder lines. In line L118-3, the two constructs appear to have integrated on separate chromosomes. After backcrossing to C57BL/6, the mouse line referred to as gBT-I.3 was established. This line contains two separately named transgenes.
  • mutations:
  • Insertion
  • synonyms:
  • Tg(TcraHsv2.3,TcrbHsv2.3)L118-3Cbn,
  • gBT-I.3,
  • gBT-I.3,
  • Tg(TcraHsv2.3,TcrbHsv2.3)L118-3Cbn
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1 Feature

Genome

1 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories