Primary Identifier | MGI:3759686 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | F10 |
Inheritance Mode | Recessive | Transmission | Germline |
Strain of Origin | 129P2/OlaHsd | Is Recombinase | false |
Is Wild Type | false |
molecularNote | Exon 8 and the polyadenylation signal were replaced with a neomycin resistance gene and a 3' partial hypoxanthine guanine phosphoribosyl transferase 1 gene. A "socket" targeting construct was used to permit subsequent knock-in. The absence of protein expression was confirmed by western blot analysis on plasma extracts. |