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Allele : Rapgef2<tm1Tkat> Rap guanine nucleotide exchange factor (GEF) 2; targeted mutation 1, Tohru Kataoka

Primary Identifier  MGI:3760242 Allele Type  Targeted
Attribute String  Conditional ready, No functional change Gene  Rapgef2
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
description  ES cell line = EB3, derived from E14TG2a. EB3 cells carry one allele of Pou5f1 that has been inactivated via targeted integration of E14TG2a ES cells with an IRESBSDpA selection cassette. J:125199 does not mention whether the null allele of Pou5f1 is also present in the line of mice created.
molecularNote  A floxed neo cassette was inserted downstream of exon 15, and an additional loxP site was inserted upstream of exon 15. A Southern blot was used to confirm the insertions.
  • mutations:
  • Insertion
  • synonyms:
  • RA-GEF-1<flox>,
  • RA-GEF-1<flox>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

0 Driven By

9 Publication categories