Primary Identifier | MGI:3760297 | Allele Type | Chemically induced (ENU) |
Gene | Gars1 | Inheritance Mode | Dominant |
Strain of Origin | BALB/cAnN | Is Recombinase | false |
Is Wild Type | false | Project Collection | Harwell ENU Mutagenesis |
molecularNote | ENU mutagenesis generated a T to C transition at base pair 456 that results in an amino acid substitution of R for C at residue 201 (C201R). Enzymatic assays confirmed a 60% drop in activity in extracts from P15 homozygotes. |