Primary Identifier | MGI:3760076 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Cdk8 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene trap vector pGT0Lxf was inserted into intron 4 and is predicted to generate a fusion protein of 163 kDa with 152 N-terminal amino acids from Cdk8 fused to 1323 amino acids of the beta-geo selection marker. The authors state that this allele is a functional null and the protein product has no kinase activity. LacZ expression was confirmed by a beta-galactosidase assay. |