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Allele : Cdk8<GT(RRS314)Byg> cyclin dependent kinase 8; gane trap RRS314, BayGenomics

Primary Identifier  MGI:3760076 Allele Type  Gene trapped
Attribute String  Null/knockout, Reporter Gene  Cdk8
Transmission  Germline Strain of Origin  129P2/OlaHsd
Is Recombinase  false Is Wild Type  false
molecularNote  The gene trap vector pGT0Lxf was inserted into intron 4 and is predicted to generate a fusion protein of 163 kDa with 152 N-terminal amino acids from Cdk8 fused to 1323 amino acids of the beta-geo selection marker. The authors state that this allele is a functional null and the protein product has no kinase activity. LacZ expression was confirmed by a beta-galactosidase assay.
  • mutations:
  • Insertion of gene trap vector
  • synonyms:
  • Cdk8<->,
  • Cdk8<->,
  • Cdk8<GT(pGT0Lxf)/Byg>,
  • Cdk8<GT(pGT0Lxf)/Byg>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories