| Primary Identifier | MGI:3760406 | Allele Type | Transgenic |
| Attribute String | Humanized sequence, Inserted expressed sequence | Gene | Tg(CD74)AR194Ayr |
| Strain of Origin | (C57BL/6J x DBA/2J)F1 x C57BL/6J | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | A vector containing the human class II-associated invariant chain gene (hIi, CD74) and promoter was injected into (C57BL/6J x DBA/2J)F1 x C57BL/6J embryos. This line (AR194) was initially backcrossed to C57BL/6-congenic invariant chain targeted mutant mice and later crossed with inbred C57BL/6 animals for a total of more than 12 generations by the donating investigator. This line no longer carries the invariant chain targeted mutation. |
