Primary Identifier | MGI:3762641 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Lgr4 |
Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
Is Recombinase | false | Is Wild Type | false |
molecularNote | Cre mediated recombination removed an Frt-flanked neo cassette and the part of exon 18 which codes for the transmembrane and signal-transducing domains. Immunostaining confirms the absence of expression in the protruding tips of the eyelids and in epithelial cells of the cornea. |