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Allele : Erc1<tm1Sud> ELKS/RAB6-interacting/CAST family member 1; targeted mutation 1, Thomas C Sudhof

Primary Identifier  MGI:3763189 Allele Type  Targeted
Attribute String  Null/knockout Gene  Erc1
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A targeting vector was designed to flank exon 3 of the gene with loxP sites and insert a FRT-flanked neomycin resistance cassette in intron 3 (within the loxP sites). Resultant carrier mice were crossed with a germline Cre transgenic strain driven by a protamine 1 (Prm1) promoter on a mixed C57BL/6 and 129 background to remove both exon 3 and the neomycin cassette.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • E1X,
  • ELKS1<nc-KO>,
  • E1X,
  • ELKS1 KO,
  • ELKS1<nc-KO>,
  • ELKS1 KO
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories