Primary Identifier | MGI:3762124 | Allele Type | Targeted |
Attribute String | Recombinase | Gene | Evx2 |
Transmission | Germline | Strain of Origin | 129S2/SvPas |
Is Recombinase | true | Is Wild Type | false |
molecularNote | A mouse Hoxd11 trangene construct was modified by in-frame insertion of the Cre coding sequence, followed by the SV40 polyadenylation signal, at the start codon in exon 1 so that Cre recombinase is expressed under control of the Hoxd11 regulatory elements, but without any residues derived from Hoxd11. Homology arms were added to target integration to a site between Hoxd13 and Evx2, at the 5' extremity of the cluster. |