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Allele : Igh-J<tm2(3H9-VDJ*)Mwg> immunoglobulin heavy chain, joining region; targeted mutation 2, Martin Weigert
Primary Identifier  MGI:3762369 Allele Type  Targeted
Gene  Igh-J Transmission  Germline
Strain of Origin  129P2/OlaHsd Is Recombinase  false
Is Wild Type  false
molecularNote  The endogenous DQ52 and all four heavy chain J elements were replaced by a rearranged heavy chain V 3H9 gene encoding an H chain of anti-dsDNA antibody with an amino acid substitution of an arginine for an aspartate at position 56 (D56R) and a neomycin resistance gene.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • VH56R,
  • 56R,
  • 56R,
  • 3H9H/56R,
  • VH56R,
  • 3H9(56R),
  • 3H9H/56R,
  • 3H9H56R,
  • 56Rki,
  • 3H9H56R,
  • 3H9(56R),
  • 56Rki
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

8 Carried By

0 Driven By

27 Publication categories





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