Primary Identifier | MGI:3762251 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(CMV-Msx2*P7H)1Rem |
Strain of Origin | (C57BL/6 x CBA)F1 | Is Recombinase | false |
Is Wild Type | false |
molecularNote | This transgene consists of a 1.1-kb fragment of the mouse Msx2 gene containing 0.3 kb of the 3.5-kb intron and a PCR-mutagenized version of the second exon bearing the Pro7His mutation under the control of human cytomegalovirus (CMV) promoter. This single base pair mutation is seen in individuals affected with Boston-type craniosynostosis. |