| Primary Identifier | MGI:3762530 | Allele Type | Targeted |
| Attribute String | Humanized sequence | Gene | Trp53 |
| Transmission | Germline | Strain of Origin | Not Specified |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A loxP site flanked neomycin resistance gene cassette and a human gene fragment containing an amino acid substitution of tryptophan for arginine at position 248 (p.R248W) replaced intron 4 through 10. The neo cassette was removed by Cre-mediated recombination. The presence of the mutations was confirmed by Southern blot and sequence analysis. |