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Allele : Trp53<tm4Xu> transformation related protein 53; targeted mutation 4, Yang Xu
Primary Identifier  MGI:3762530 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Trp53
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette and a human gene fragment containing an amino acid substitution of tryptophan for arginine at position 248 (p.R248W) replaced intron 4 through 10. The neo cassette was removed by Cre-mediated recombination. The presence of the mutations was confirmed by Southern blot and sequence analysis.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • p53<R248W>,
  • p53<R248W>
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

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9 Publication categories

Trail: Allele




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