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Allele : Trp53<tm5Xu> transformation related protein 53; targeted mutation 5, Yang Xu

Primary Identifier  MGI:3762531 Allele Type  Targeted
Attribute String  Humanized sequence Gene  Trp53
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A loxP site flanked neomycin resistance gene cassette and a human gene fragment containing an amino acid substitution of histidine with arginine at position 273 (p.R273H) replaced intron 4 through 10. The neo cassette was removed by cre-mediated recombination. The presence of the mutations was confirmed by Southern blot and sequence analysis.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • p53<R273H>,
  • p53<R273H>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories