| Primary Identifier | MGI:3762770 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Cd274 |
| Transmission | Germline | Strain of Origin | 129S/SvEvBrd |
| Is Recombinase | false | Is Wild Type | false |
| Project Collection | Lexicon |
| molecularNote | By homologous recombination a loxP site was inserted 5' of exon2, followed by a NeoR cassette and a 3' loxP site. The resulting mutant mice, Cd274tm1Lex, were crossed with protamine-Cre transgenic mice to delete exon 2 containing the translational start site. Flow cytometric protein expression analysis confirmed absence of targeted protein expression. |
