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Allele : Pdcd1lg2<tm1.1Lex> programmed cell death 1 ligand 2; targeted mutation 1.1, Lexicon Genetics

Primary Identifier  MGI:3762772 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pdcd1lg2
Transmission  Germline Strain of Origin  129S/SvEvBrd
Is Recombinase  false Is Wild Type  false
Project Collection  Lexicon
molecularNote  By homologous recombination a loxP site was inserted 5' of exon2, followed by a NeoR cassette and a 3' loxP site. The resulting mutant mice, Pdcd1lg2tm1Lex were crossed with protamine-Cre transgenic mice to delete exon 2 containing the translational start site. Flow cytometric protein expression analysis confirmed absence of targeted protein expression.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • PD-L2<->,
  • PD-L2<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories

Trail: Allele