| Primary Identifier | MGI:3763367 | Allele Type | Targeted |
| Attribute String | Modified regulatory region, Null/knockout | Gene | Tead2 |
| Transmission | Germline | Strain of Origin | 129X1/SvJ |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | The enhancer located upstream of exon 2, exon 2 and exon 3 were removed by cre-mediated recombination. These regions are responsible for encoding the N-terminal 99 amino acids of the protein thereby removing the translation initiation site and 82% of the TEA domain. Reduction in transcript production was confirmed by northern blot analysis on RNA extracted from lungs. |
