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Allele : Ctsk<tm1(cre)Ska> cathepsin K; targeted mutation 1, Shigeaki Kato

Primary Identifier  MGI:3764465 Allele Type  Targeted
Attribute String  Null/knockout, Recombinase Gene  Ctsk
Transmission  Germline Strain of Origin  (C57BL/6NCrlj x CBA/JNCrlj)F1
Is Recombinase  true Is Wild Type  false
molecularNote  A cre recombinase gene and a downstream frt-flanked kanamycin/neomycin resistance gene was inserted into the endogenous ATG start site of the gene, replacing the first four exons. Chimeric mice were crossed with a deleter strain to remove the selection cassette. Cre expression in heterozygotes was detected in mature osteoclasts but not osteoblasts when crossed with a tester strain.
  • mutations:
  • Insertion
  • synonyms:
  • CtsKCre,
  • CatK<Cre>,
  • Cathepsin K-Cre,
  • Cathepsin K-Cre,
  • Ctsk<Cre>,
  • CtsKCre,
  • Ctsk<Cre>,
  • CatK<Cre>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

1 Driven By

90 Publication categories