| Primary Identifier | MGI:3764465 | Allele Type | Targeted |
| Attribute String | Null/knockout, Recombinase | Gene | Ctsk |
| Transmission | Germline | Strain of Origin | (C57BL/6NCrlj x CBA/JNCrlj)F1 |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A cre recombinase gene and a downstream frt-flanked kanamycin/neomycin resistance gene was inserted into the endogenous ATG start site of the gene, replacing the first four exons. Chimeric mice were crossed with a deleter strain to remove the selection cassette. Cre expression in heterozygotes was detected in mature osteoclasts but not osteoblasts when crossed with a tester strain. |
