| Primary Identifier | MGI:3764913 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ep400 |
| Transmission | Germline | Strain of Origin | (129X1/SvJ x 129S1/Sv)F1-Kitl<+> |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Part of exon and intron 2 were replaced with a neo cassette. The absence of transcript was confirmed by whole mount in situ hybridization using E8.5 embryos. An aberrant transcript lacking the 471 N-terminal amino acids is produced from an initiation site in exon 3. The lack of the full-length protein product and presence of a shorter peptide lacking the N-terminus was confirmed by western blot analysis on embryonic fibroblasts derived from E8.5 embryos. |
