| Primary Identifier | MGI:3766089 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(COL1A1)73Prc |
| Strain of Origin | FVB/N | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | These mice express a mini-gene construct that contains the 5'- and 3'-ends of the human gene for the pro-alpha(1) collagen chain but lack a large central region containing 41 exons. The mini-gene includes 2.5 kilobases of the 5'-promoter region, the first 5 exons and introns, the last 6 exons and introns, and about 2 kilobases of the 3"flanking region. The junction between the 5'- and 3'-halves of the mini-gene was made in introns so as to preserve the consensus sequences for RNA splicing. Mice in this line carry about 20 copies of the transgene. |
