Primary Identifier | MGI:3766574 | Allele Type | Targeted |
Attribute String | Null/knockout | Gene | Del(11Chad-Hoxb1)19Brd |
Transmission | Germline | Strain of Origin | 129S7/SvEvBrd-Hprt1<b-m2> |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A loxP site was targeted into the Chad gene. A second loxP site was targeted in cis into the Hoxb1 gene. Transient expression of Cre recombinase in ES cells resulted in recombination between loxP sites on the same chromosome, deleting the 1.8 Mb region from Chad to Hoxb1. |