| Primary Identifier | MGI:3766932 | Allele Type | Targeted |
| Attribute String | Recombinase | Gene | Gt(ROSA)26Sor |
| Transmission | Germline | Strain of Origin | 129S4/SvJaeSor |
| Is Recombinase | true | Is Wild Type | false |
| molecularNote | A targeting construct with the SA-PhiC31opA-PGKneopA cassette, which contains the mouse codon-optimized site-specific recombinase PhiC31o sequence (with a C-terminal SV40 nuclear localization signal) driven by the phosphoglycerate kinase 1 (PGK) promoter, and bovine growth hormone polyadenylation (bpA) sequence was inserted into the Gt(ROSA)26Sor locus. Flp-mediated recombination removes the neo cassette. PhiC31o-mediated recombination in mice carrying containing a sequence of interest flanked by attB and attP sites results in tissue-specific deletion of the targeted sequence. |
