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Allele : Sell<tm2Alb> selectin, lymphocyte; targeted mutation 2, Arthur L Beaudet

Primary Identifier  MGI:3767069 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sell
Transmission  Germline Strain of Origin  129S7/SvEvBrd-Hprt1<b-m2>
Is Recombinase  false Is Wild Type  false
molecularNote  The Sell gene was disrupted by insertion of a puromycin resistance cassette in opposite orientation into the coding sequence via homologous recombination. The construct was injected into ES cells already carrying mutations in Sele and Selp. Clones where the targeting vector inserted in cis to the Sele and Selp mutations were used to produce triple selectin-null mutant mice.
  • mutations:
  • Insertion,
  • Intragenic deletion
  • synonyms:
  • E/P/I,
  • E/P/I
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

7 Publication categories