| Primary Identifier | MGI:3765968 | Allele Type | Targeted |
| Attribute String | Null/knockout | Gene | Ltbp1 |
| Transmission | Germline | Strain of Origin | (129S6/SvEvTac x C57BL/6NTac)F1 |
| Is Recombinase | false | Is Wild Type | false |
| description | Ltbp1tm1Veto and Ltbp1tm2Veto mice exhibit identical defects. |
| molecularNote | A 7.8 kb fragment from codon 165 in exon 2 through exon 2 and its downstream intron were deleted and replaced with a lacZ gene and neo cassette using Velocigene technology. The neo cassette was removed by cre-mediated recombination. The absence of protein was confirmed by western blot analysis on protein extracts from E14.5 hearts. |
