Primary Identifier | MGI:3768254 | Allele Type | Gene trapped |
Attribute String | Null/knockout, Reporter | Gene | Chst11 |
Transmission | Germline | Strain of Origin | Not Specified |
Is Recombinase | false | Is Wild Type | false |
molecularNote | The gene trap vector PT-1 was inserted into intron 1 resulting in a fusion transcript encoding exon1 and lacZ. LacZ expression was monitored by beta-galactosidase assay. Expression analysis confirmed the lack of expression of exons 2 and 3 and reduced protein function was monitored by increasing En2 expression. This allele is likely to be a null allele. |