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Allele : Mapt<tm1(MAPT)Vln> microtubule-associated protein tau; targeted mutation 1, Fred Van Leuven

Primary Identifier  MGI:3768527 Allele Type  Targeted
Attribute String  Humanized sequence, Inserted expressed sequence, Modified isoform(s), Null/knockout Gene  Mapt
Transmission  Germline Strain of Origin  Not Specified
Is Recombinase  false Is Wild Type  false
molecularNote  A human MAPT cDNA encoding the longest tau isoform of 441 amino acids containing four repeats, with 2 N-terminal inserts replaced the endogenous mouse gene. Endogenous mouse Mapt protein is not expressed, and the inserted human gene is expressed in brain driven by a murine Thy1 promoter beginning at P15.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • tau-KOKI,
  • tau-KOKI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories