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Allele : Stat3<tm1.1Xyfu> signal transducer and activator of transcription 3; targeted mutation 1.1, Xin-Yuan Fu

Primary Identifier  MGI:3768533 Allele Type  Targeted
Attribute String  Null/knockout Gene  Stat3
Transmission  Germline Strain of Origin  129S1/Sv-Oca2<+> Tyr<+> Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  Cre-mediated recombination was used to delete exons 18, 19 and 20. These exons encode an SH2 domain essential for protein function. The absence of protein product was confirmed by western blot on liver tissue.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Stat3<D>,
  • Stat3<D>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories