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Allele : Tgfb3<tm2(Tgfb1)Vk> transforming growth factor, beta 3; targeted mutation 2, Vesa Kaartinen

Primary Identifier  MGI:3768675 Allele Type  Targeted
Attribute String  Inserted expressed sequence, Null/knockout Gene  Tgfb3
Transmission  Germline Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+>
Is Recombinase  false Is Wild Type  false
molecularNote  A vector containing Tgfb1 cDNA followed by a pgk polyA sequence and a loxP flanked neomycin resistance cassette was inserted into the ATG start site of the targeted gene. Quantitative RT-PCR of RNA isolated from the tips of the palatal shelves demonstrates high Tgfb1 expression but no Tgfb3 expression in homozygotes.
  • mutations:
  • Insertion
  • synonyms:
  • Tgfb1-KI,
  • Tgfb1-KI
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

4 Publication categories