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Allele : Tg(tetO-Creb1*S133A)1Rdu transgene insertion 1, Ronald S Duman

Primary Identifier  MGI:3767676 Allele Type  Transgenic
Attribute String  Inducible, Inserted expressed sequence Gene  Tg(tetO-Creb1*S133A)1Rdu
Strain of Origin  C57BL/6 x SJL Induced With  doxycycline/tetracycline
Is Recombinase  false Is Wild Type  false
molecularNote  A rat Creb1 cDNA was mutated at codon 133 to alter the endcoded serine to an alanine. In addition, a FLAG-tag peptide was added at the N-terminus to distinguish the expressed protein from the endogenous protein. The modified cDNA was cloned into an expression vector containing a tetracycline responsive element (TetOP) and a CMV minimal promoter.
  • mutations:
  • Insertion
  • synonyms:
  • TetOp-mCREB,
  • TetOp-mCREB
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

5 Publication categories