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Allele : Tg(Prnp-MAPT*P301S)PS19Vle transgene insertion PS19, Virginia M Y Lee
Primary Identifier  MGI:3768407 Allele Type  Transgenic
Attribute String  Humanized sequence, Inserted expressed sequence Gene  Tg(Prnp-MAPT*P301S)PS19Vle
Strain of Origin  (C57BL/6 x C3H)F1 Is Recombinase  false
Is Wild Type  false
molecularNote  The transgene construct contains the P301S mutant human microtubule-associated protein tau, MAPT, under the direction of the mouse prion protein, Prnp, promoter. The expression of the mutant human MAPT is 5-fold higher than the expression of the endogenous mouse Mapt protein. Transgene insertion occurred on Chr 3, causing a 249 Kb deletion.
  • mutations:
  • Insertion,
  • Intergenic deletion
  • synonyms:
  • PS19 Tg,
  • PS19 Tg,
  • P301S tau (line PS19),
  • P301S tau (line PS19)
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

4 Carried By

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0 Driven By

307 Publication categories

Trail: Allele




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