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Transgene : Tg(Prnp-MAPT*P301S)PS19Vle transgene insertion PS19, Virginia M Y Lee
Primary Identifier  MGI:3768406 Organism  mouse, laboratory
Chromosome  3 Mgi Type  transgene
description  PHENOTYPE: Mice show progressive accumulation of tau lesions from 6 months of age, along with brain atrophy, motor deficits, and defects in CNS transmission. The mice may be useful for study of Alzhemimer Disease and related tauopathies. [provided by MGI curators]
  • synonyms:
  • transgene insertion PS19, Virginia M Y Lee,
  • P301S tau (line PS19),
  • Tg(Prnp-MAPT*P301S)PS19Vle,
  • PS19 Tg
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