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Allele : Sirt3<tm1.1Fwa> sirtuin 3; targeted mutation 1.1, Frederick W Alt

Primary Identifier  MGI:3769234 Allele Type  Targeted
Attribute String  Null/knockout Gene  Sirt3
Transmission  Germline Strain of Origin  129S6/SvEvTac
Is Recombinase  false Is Wild Type  false
molecularNote  A floxed neo cassette was inserted into intron 3 and an additional loxP site was inserted upstream of exon 2. Cre-mediated recombination was used to remove the neo cassette, exon 2 and exon 3. The absence of protein product was confirmed by western blot analysis on liver and brain extracts.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Sirt3<->,
  • Sirt3<->
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1 Feature

Trail: Allele

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

110 Publication categories

Trail: Allele