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Allele : Ptf1a<tm2Macd> pancreas specific transcription factor, 1a; targeted mutation 2, Raymond MacDonald
Primary Identifier  MGI:3771319 Allele Type  Targeted
Gene  Ptf1a Transmission  Germline
Strain of Origin  (129X1/SvJ x 129S1/Sv)F1-Kitl<+> Is Recombinase  false
Is Wild Type  false
molecularNote  Tryptophan codon 298 (TGG) in exon 2 was changed to alanine (GCG) (p.W298A) by RMCE using (ES) cells containing the Ptf1atm1Mgn allele. The exchange cassette contained the Ptf1a gene SalI-SalI fragment from strain 129 genomic DNA with the codon 298 mutation.
  • mutations:
  • Nucleotide substitutions
  • synonyms:
  • Ptf1a(W298A),
  • Ptf1a<tm1.2<W298AMacd>,
  • Ptf1a<WA>,
  • Ptf1a<tm1.2<W298AMacd>,
  • Ptf1a<WA>,
  • Ptf1a(W298A)
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories





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