Primary Identifier | MGI:3769767 | Allele Type | Transgenic |
Attribute String | Inserted expressed sequence | Gene | Tg(Igh-Lmp2a)13FRdni |
Strain of Origin | C57BL/6 x SJL | Is Recombinase | false |
Is Wild Type | false |
description | 9 lines were created with the eight others exhibiting lymphocyte cell lineage defects. Line 13F results in a deletion in chromosome 7 from Mkrn3 to Herc2 (Mkrn3, Ndn, Snurf/Snrpn, Ube3a, and Herc2 are deleted). |
molecularNote | The Ig heavy chain promoter with Emu enhancer element was used to drive the expression of the Epstein-Barr virus latent membrane protein 2A. Expression was confirmed by RT-PCR of brain extracts. |