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Allele : Tg(Myh6-NFKBIA*S32A*S36A)17Kykj transgene insertion 17, W Keith Jones
Primary Identifier  MGI:3771152 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Myh6-NFKBIA*S32A*S36A)17Kykj
Strain of Origin  FVB/N Is Recombinase  false
Is Wild Type  false
molecularNote  The 1.1 kb human NFKBIA cDNA with two introduced point mutations at codons 32 and 36 (resulting in amino acid changes S32A and S36A) was subcloned between the 5.5 kb alpha-myosin heavy chain promoter and the 736 bp human growth hormone (Hgh) polyadenylation signal. Five founders with 1, 2 (line 17), 7 (line 44), 4 (line 151), and 7 (line 159) copies of the transgene were identified, but no offspring from the single copy number founder were obtained.
  • mutations:
  • Insertion
  • synonyms:
  • 2M,
  • TgN(IKBABD)17-Kykj,
  • TgN(IKBABD)17-Kykj,
  • 2M
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

8 Publication categories

Trail: Allele




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