| Primary Identifier | MGI:3771966 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(TTR-Igf1)1Jxu |
| Strain of Origin | C57BL/6 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | The transgene construct consists of the enhancer/promoter of the TTR gene, the mouse Igf1 cDNA, and the SV40t polyadenylation-signaling sequence. The IGF-I transgene was flanked with a tandem repeat of the HS4 chromosomal insulator sequence from the 5' region of the chicken beta-globin gene. This line carries approximately three copies of the transgene construct. This line expresses Igf1 at 3x the endogenous level in the liver. |
