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Allele : Klra8<Cmv1-del> killer cell lectin-like receptor, subfamily A, member 8; cytomegalovirus resistance 1, deletion

Primary Identifier	MGI:3773165	Gene	Klra8
Inheritance Mode	Recessive	Strain of Origin	BXD8/TyJ
Is Recombinase	false	Is Wild Type	false

molecularNote

Mapping experiments identified a 23 kb deletion in the Klra cluster in the BXD-8/Ty strain that contained only the Klra8 gene. This deletion correlated with an increased susceptiblity to cytomegalovirus infection.

mutations:
Intragenic deletion

synonyms:
Klra8<KO>,
L49h<->,
L49h<->,
Klra8<KO>

earliestPublication:
Scalzo AA, et al. (1992) The effect of the Cmv-1 resistance gene, which is linked to the natural killer cell gene complex, is mediated by natural killer cells. J Immunol 149(2):581-9

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

2 Carried By

0 Driven By

40 Publication categories

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