Primary Identifier | MGI:3772938 | Allele Type | Transgenic |
Attribute String | Inducible, Inserted expressed sequence | Gene | Tg(tetO-Clock)1Jt |
Strain of Origin | C57BL/6 | Induced With | doxycycline/tetracycline |
Is Recombinase | false | Is Wild Type | false |
molecularNote | A transgenic vector was designed to carry the full-length wildtype mouse Clock gene downstream of a tetracycline-responsive promoter (TRE; tetO). Crossing these mice with mice expressing the tTA or reverse tetracycline-controlled transactivator protein under control of tissue-specific promoters, transgene expression can be regulated in appropriate tissues in the offspring with administration of the tet analog doxycycline. |