| Primary Identifier | MGI:3774320 | Allele Type | Targeted |
| Attribute String | Hypomorph | Gene | Ntrk2 |
| Transmission | Germline | Strain of Origin | 129P2/OlaHsd |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A cDNA encoding the open reading frame with an A to T transversion at position 2958 that resulted in an amino acid substitution of phenylalanine for tyrosine at position 816 (Y816F) was inserted into the coding exon. A floxed neo cassette was also inserted downstream of the cDNA but was removed by subsequent germ-line, cre-mediated recombination. The amino acid substitution occures within the PLCgamma site. |
