|  Help  |  About  |  Contact Us

Allele : Pbx3<tm1.1Og> pre B cell leukemia homeobox 3; targeted mutation 1.1, Stephen O'Gorman

Primary Identifier  MGI:3773270 Allele Type  Targeted
Attribute String  Null/knockout Gene  Pbx3
Transmission  Germline Strain of Origin  129S4/SvJae-Tg(Prm-cre)70Og
Is Recombinase  false Is Wild Type  false
molecularNote  A neo cassette with a 5' loxP site was inserted into intron 3 and an additional loxP site was inserted into intron 2. Targeting took place in PC3 ES cells homozygous for Tg(Prm-cre)70Og. Cre-recombinase under control of the male-germline specific protamine promoter resulted in the removal of exon 3 upon transmission from male chimeras. The authors state that this is a null allele.
  • mutations:
  • Intragenic deletion
  • synonyms:
  • Pbx3N,
  • Pbx3N
Quick Links:
 
Quick Links:
 

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

4 Publication categories