| Primary Identifier | MGI:3773271 | Allele Type | Targeted |
| Attribute String | Conditional ready, No functional change | Gene | Pbx3 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae-Tg(Prm-cre)70Og |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | A neo cassette with a 5' loxP site was inserted into intron 3 and an additional loxP site was inserted into intron 2. Targeting took place in PC3 ES cells, which are homozygous for Tg(Prm-cre)70Og, a cre transgene active only in haploid spermatids. A minority of the alleles created from this construct exhibited a deficiency of cre-mediated recombination driven by the male-germline specific protamine promoter in male germ cells and transmitted the conditional allele through male chimeric mice. |
