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Allele : Prrx1<tm1Bhr> paired related homeobox 1; targeted mutation 1, Richard R Behringer
Primary Identifier  MGI:3773688 Allele Type  Targeted
Attribute String  Modified regulatory region Gene  Prrx1
Transmission  Germline Strain of Origin  129S4/SvJae-Tg(Prm-cre)70Og
Is Recombinase  false Is Wild Type  false
molecularNote  Targeting took place in ES cells homozyogus for the cre transgene Tg(Prm-cre)70Og, which expresses Cre recombinase only in haploid spermatids. The Carollia (bat) limb enhancer element was used to replace the endogenous mouse enhancer upstream of exon 1 and a floxed neo cassette was inserted into intron 1. Cre-mediated excision removed the neo cassette upon transmission from male chimeric mice.
  • mutations:
  • Intragenic deletion,
  • Insertion
  • synonyms:
  • Prx1<BatE>,
  • Prx1<BatE>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

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0 Driven By

4 Publication categories





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