| Primary Identifier | MGI:3773688 | Allele Type | Targeted |
| Attribute String | Modified regulatory region | Gene | Prrx1 |
| Transmission | Germline | Strain of Origin | 129S4/SvJae-Tg(Prm-cre)70Og |
| Is Recombinase | false | Is Wild Type | false |
| molecularNote | Targeting took place in ES cells homozyogus for the cre transgene Tg(Prm-cre)70Og, which expresses Cre recombinase only in haploid spermatids. The Carollia (bat) limb enhancer element was used to replace the endogenous mouse enhancer upstream of exon 1 and a floxed neo cassette was inserted into intron 1. Cre-mediated excision removed the neo cassette upon transmission from male chimeric mice. |