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Allele : Tg(Tcrb)HRBAll transgene insertion HRB, James P Allison

Primary Identifier  MGI:3773739 Allele Type  Transgenic
Attribute String  Inserted expressed sequence Gene  Tg(Tcrb)HRBAll
Strain of Origin  either: C57BL/6 or (CBA x C57BL/6)F2 Is Recombinase  false
Is Wild Type  false
molecularNote  Rearranged Vbeta8.3-SGTGGSAETL TCRbeta chain was cloned from a population of CD8+ T cells that recognizes a 17-mer peptide from the C-terminus of Histone 4 family members presented on H2-Kb. The recombined gene segments were placed in a TCR expression vector and injected into blastocytes. This founder line contains only the beta chain transgene, which is functionally expressed in about 25% of CD8+ T cells.
  • mutations:
  • Insertion
  • synonyms:
  • HRB TCR,
  • HRB TCR
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1 Feature

Trail: Allele

Genome

1 Expresses

Trail: Allele

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

2 Carried By

Trail: Allele

0 Driven By

3 Publication categories

Trail: Allele