| Primary Identifier | MGI:3773740 | Allele Type | Transgenic |
| Attribute String | Inserted expressed sequence | Gene | Tg(Tcra,Tcrb)HRVAll |
| Strain of Origin | either: C57BL/6 or (CBA x C57BL/6)F2 | Is Recombinase | false |
| Is Wild Type | false |
| molecularNote | Rearranged Valpha2-SGTGGYKV TCRalpha and Vbeta8.3-SGTGGSAETL TCRbeta chains were cloned from a population of CD8+ T cells that recognizes a 17-mer peptide from the C-terminus of Histone 4 family members presented on H2-Kb. The recombined gene segments were placed in a TCR expression vector and injected into blastocytes. This founder line is characterized by "variegated" expression of the transgenic TCR with about 28% of CD8+ T cells expressing the transgenic TCR. |
