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Allele : Sh2d1a<tm2Vei> SH2 domain containing 1A; targeted mutation 2, Andre Veillette

Primary Identifier	MGI:3774546	Allele Type	Targeted
Attribute String	Conditional ready, No functional change	Gene	Sh2d1a
Transmission	Germline	Strain of Origin	Not Specified
Is Recombinase	false	Is Wild Type	false

molecularNote

An frt-flanked neo cassette with a 5' loxP site was inserted upstream of exon 2 and an additional loxP site was inserted downstream of exon 2. The neo cassette ws removed by flp-mediated recombination.

mutations:
Insertion

cellLines:
Not Specified

synonyms:
sap<fl>,
sap<fl>

earliestPublication:
Veillette A, et al. (2008) SAP expression in T cells, not in B cells, is required for humoral immunity. Proc Natl Acad Sci U S A 105(4):1273-8

1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

Other

0 Carried By

0 Driven By

5 Publication categories

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