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Allele : Shh<tm6Amc> sonic hedgehog; targeted mutation 6, Andrew P McMahon

Primary Identifier  MGI:3775846 Allele Type  Targeted
Attribute String  Null/knockout, Reporter Gene  Shh
Transmission  Germline Strain of Origin  129X1/SvJ
Is Recombinase  false Is Wild Type  false
molecularNote  A GFP cassette was inserted into exon 3 and an FRT site flanked neomycin resistance gene cassette was inserted between exon 2 and 3. The presence of the fusion protein and the absence of the endogenous product was confirmed by western blot analysis on E9.5 embryo extracts. This allele produces functional albeit inefficient protein product.
  • mutations:
  • Insertion
  • synonyms:
  • Shh::GFP,
  • Shh::GFP
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

3 Carried By

0 Driven By

10 Publication categories