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Allele : Tcf3<tm1Xhsu> transcription factor 3; targeted mutation 1, Xioa-Hong Sun

Primary Identifier  MGI:3776793 Allele Type  Targeted
Gene  Tcf3 Transmission  Germline
Strain of Origin  129X1/SvJ Is Recombinase  false
Is Wild Type  false
molecularNote  Exon 13 was replaced with an exon 13 containing point mutations followed by a floxed neo cassette. The neo cassette was removed by germ-line, cre-meditated recombination. The point mutations in exon 13 occur in the MAPK sites and render the protein product resistant to Notch-induced degradation.
  • mutations:
  • Nucleotide substitutions,
  • Insertion
  • synonyms:
  • E2A<M>,
  • E2A<M>
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

1 Carried By

0 Driven By

5 Publication categories