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Allele : Tg(Lck-Stat5b*)1Mafa transgene insertion 1, Michael A Farrar

Primary Identifier  MGI:3776805 Allele Type  Transgenic
Attribute String  Constitutively active, Inserted expressed sequence Gene  Tg(Lck-Stat5b*)1Mafa
Is Recombinase  false Is Wild Type  false
molecularNote  The Lck promoter with the Emu enhancer drives expression of a cDNA encoding a constitutively active Stat5b with point mutations that result in replacement of histidine with arginine at position 299 and serine with phenylalanine at position 711. This mutation results in constitutive phosphorylation of tyrosine 699.
  • mutations:
  • Insertion
  • synonyms:
  • STAT5b-CA,
  • STAT5b-CA,
  • CA-STAT5,
  • CA-STAT5
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1 Feature

Genome

0 Expresses

0 Mutation Involves

Phenotype

Mouse alleles --> Mammalian phenotypes (MP terms)

 

Other

0 Carried By

0 Driven By

32 Publication categories